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Axel Methner Selected Research

Nervous System Heredodegenerative Disorders

2/2017Tetrahydrocarbazoles decrease elevated SOCE in medium spiny neurons from transgenic YAC128 mice, a model of Huntington's disease.
1/2013Expression of genes encoding the calcium signalosome in cellular and transgenic models of Huntington's disease.

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Axel Methner Research Topics

Disease

4Neurodegenerative Diseases (Neurodegenerative Disease)
08/2020 - 04/2013
4Multiple Sclerosis
01/2019 - 02/2013
3Parkinson Disease (Parkinson's Disease)
01/2020 - 08/2006
3Neoplasms (Cancer)
01/2018 - 09/2011
3Huntington Disease (Huntington's Disease)
01/2018 - 01/2013
2Polyneuropathies (Polyneuropathy)
01/2022 - 10/2019
2Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy)
10/2019 - 01/2012
2Psoriasis (Pustulosis Palmaris et Plantaris)
01/2019 - 12/2017
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2019 - 01/2017
2Inflammation (Inflammations)
10/2018 - 04/2016
2Alzheimer Disease (Alzheimer's Disease)
06/2018 - 06/2004
2Mitochondrial Diseases (Mitochondrial Disease)
01/2018 - 04/2014
2Traumatic Brain Injuries (Traumatic Brain Injury)
12/2017 - 08/2014
2Ganglion Cysts (Ganglion)
07/2017 - 01/2012
2Nervous System Heredodegenerative Disorders
02/2017 - 01/2013
2Relapsing-Remitting Multiple Sclerosis
01/2017 - 07/2012
2Breast Neoplasms (Breast Cancer)
07/2016 - 01/2011
2Ischemia
08/2014 - 01/2005
2Epilepsy (Aura)
06/2014 - 12/2011
2Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
04/2014 - 10/2009
1Muscular Diseases (Myopathy)
10/2022
1Obesity
01/2020
1Insulin Resistance
01/2020
1Autoimmune Diseases (Autoimmune Disease)
01/2019
1Coronary Artery Disease (Coronary Atherosclerosis)
10/2018
1Body Weight (Weight, Body)
12/2017
1Pseudotumor Cerebri (Idiopathic Intracranial Hypertension)
07/2017
1Papilledema
07/2017
1Atrophy
07/2017
1Demyelinating Diseases (Demyelinating Disease)
01/2017
1Disease Progression
01/2017
1Hepatocellular Carcinoma (Hepatoma)
07/2016
1Restless Legs Syndrome (Restless Legs)
07/2016
1Optic Neuritis (Retrobulbar Neuritis)
04/2016
1Retinal Degeneration
04/2016
1Infarction (Infarctions)
08/2015
1Retinal Artery Occlusion
08/2015
1Pelizaeus-Merzbacher Disease
08/2015
1Gliosis
08/2015
1Heart Arrest (Cardiac Arrest)
08/2014
1Stroke (Strokes)
08/2014
1Glioblastoma (Glioblastoma Multiforme)
06/2014
1Neurocognitive Disorders (Clerambault Syndrome)
12/2013
1Abscess
11/2012
1Hepatolenticular Degeneration (Wilson's Disease)
01/2012
1Fibrosis (Cirrhosis)
01/2012
1Parkinsonian Disorders (Parkinsonism)
01/2012
1Type 4A Charcot-Marie-Tooth disease
01/2012
1Temporal Lobe Epilepsy
12/2011
1Neoplasm Metastasis (Metastasis)
09/2011

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
01/2020 - 12/2011
8Glutathione (Reduced Glutathione)IBA
01/2019 - 08/2006
6CalciumIBA
10/2022 - 12/2011
6Retinaldehyde (Retinal)IBA
07/2017 - 01/2012
5Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 09/2011
4Dimethyl FumarateIBA
01/2019 - 07/2012
4Glutamic Acid (Glutamate)FDA Link
01/2018 - 10/2009
3Glucose (Dextrose)FDA LinkGeneric
01/2020 - 01/2003
2Biomarkers (Surrogate Marker)IBA
10/2018 - 04/2016
2polyglutamineIBA
02/2017 - 01/2013
2Oxygen (Dioxygen)IBA
08/2014 - 01/2003
2AntiportersIBA
06/2014 - 04/2013
2Cystine (L-Cystine)IBA
06/2014 - 04/2013
1Mitochondrial Permeability Transition PoreIBA
10/2022
1GDAP proteinIBA
01/2022
1Glutathione Transferase (Glutathione S-Transferase)IBA
01/2022
1Probucol (Lorelco)FDA Link
08/2020
1IsotopesIBA
01/2020
1Adenosine Triphosphate (ATP)IBA
10/2019
1GTP Phosphohydrolases (GTPases)IBA
10/2019
1Messenger RNA (mRNA)IBA
10/2018
1Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA
10/2018
1Presenilin-1IBA
06/2018
1PresenilinsIBA
06/2018
1Therapeutic UsesIBA
01/2018
1AntioxidantsIBA
01/2018
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
01/2018
1IronIBA
01/2018
1Homer Scaffolding Proteins (Homer 1)IBA
01/2018
1Metformin (Glucophage)FDA LinkGeneric
01/2018
11-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)IBA
01/2018
1NAD (NADH)IBA
01/2018
1AndrogensIBA
07/2016
1Transcription Factors (Transcription Factor)IBA
07/2016
1CurcuminIBA
08/2015
1Cysteine (L-Cysteine)FDA Link
06/2014
1Peptide Initiation Factors (Initiation Factor)IBA
06/2014
1Phosphatidylinositols (Phosphatidylinositol)IBA
06/2014
1Activating Transcription Factor 4IBA
06/2014
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
06/2014
1Biological ProductsIBA
06/2014
1env Gene ProductsIBA
12/2013
1Potassium Channels (Potassium Channel)IBA
02/2013
1Pharmaceutical PreparationsIBA
02/2013
1Anti-Bacterial Agents (Antibiotics)IBA
11/2012
1CopperIBA
01/2012
1Sodium-Hydrogen ExchangersIBA
09/2011

Therapy/Procedure

6Therapeutics
01/2018 - 08/2006
1Oral Administration
12/2017
1Lasers (Laser)
08/2015